产品货号:
Z34594
中文名称:
Serpin C1/Antithrombin III/SERPINC1抗体
英文名称:
Anti-Serpin C1/Antithrombin III/SERPINC1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Serpin C1/Antithrombin III/SERPINC1 Antibody |
指标别名 | Antithrombin;Antithrombin III;AT3;ATIII;Serpin C1;SERPINC1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ICC/IF |
基因名称 | SERPINC1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human SERPINC1 Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade.AT-III inhibits thrombin as well as factors IXa,Xa and XIa.Its inhibitory activity is greatly enhanced in the presence of heparin. |
实际分子量 | 53KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Serpin peptidase inhibitor,clade C(antithrombin),member 1,also known as Antithrombin III(AT3) is the most important inhibitor of thrombin OMBIN III and other coagulation proteinases.This gene is mapped to 1q25.1.The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily.This protein inhibits thrombin as well as other activated serine proteases of the coagulation system,and it regulates the blood coagulation cascade.The protein includes two functional domains:the heparin binding-domain at the N-terminus of the mature protein,and the reactive site domain at the C-terminus.The inhibitory activity is enhanced by the presence of heparin.More than 120 mutations have been identified for this gene,many of which are known to cause antithrombin-III deficiency. |
Uniprot ID | P01008 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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